MLB on TBS Tuesday Night Regular Season Finale to Showcase NL’s Current Final Wild Card Holder – Philadelphia Phillies vs. AL No. 1 Seed Houston Astros – in Full National Telecast, Tuesday, Oct. 4, at 8 p.m. ET
| Date | Time (ET) | Program / Commentators |
| Oct. 4 | 7:30 p.m. | MLB on TBS Leadoff Pedro Martinez, Jimmy Rollins, Curtis Granderson & Ernie Johnson |
| 8 p.m. | Philadelphia Phillies* vs. Houston Astros* (* = available locally) Brian Anderson, Ron Darling, Jeff Francoeur & Lauren Shehadi | |
| Postgame | MLB on TBS Closer Martinez, Rollins, Granderson & Johnson |
MLB on TBS Game Storylines
- TBS telecast will be fully available nationally (will co-exist in the Philadelphia & Houston markets)
- Houston has a Magic Number of 1 clinch the AL’s No. 1 seed and will receive a bye into the ALDS
- The #1 seed will play the winner of the #4 vs. #5 Wild Card series in the ALDS
- Philadelphia is looking to clinch its first Postseason appearance since 2011
- The Phillies are currently the No. 6 seed (83-71, +0.5 games over Milwaukee) and would play the St. Louis Cardinals in the Wild Card round
Following the regular season, TBS will serve as the exclusive home of the 2022 American League Division Series (ALDS) and American League Championship Series (ALCS), with ALDS coverage beginning Tuesday, Oct. 11. This season marked the start of a new seven-year rights agreement between Turner Sports and Major League Baseball including a season-long regular season slate and extended coverage of the MLB Postseason. The current multimedia rights agreement extends the partnership between Turner Sports and MLB to more than 50 years. The partnership represents one of the longest-running relationships between a media company and league in the history of televised sports, dating back to 1973 when MLB games were first televised on WTCG (now TBS).