MLB on TBS Tuesday Night to Showcase Doubleheader Featuring Postseason Contenders – Houston Astros vs. Tampa Bay Rays & St. Louis Cardinals vs. San Diego Padres – Tomorrow, Tuesday, Sept. 20, Beginning at 6:30 p.m. ET
| Date | Time (ET) | Program / Commentators |
| Sept. 20 | 6 p.m. | MLB on TBS Leadoff Pedro Martinez, Jimmy Rollins, Curtis Granderson & Ernie Johnson |
| 6:30 p.m. | Houston Astros vs. Tampa Bay Rays Brian Anderson, Ron Darling & Lauren Shehadi | |
| 9:30 p.m. | St. Louis Cardinals vs. San Diego Padres Don Orsillo, Jeff Francoeur & Matt Winer | |
| Postgame | MLB on TBS Closer Martinez, Rollins, Granderson & Johnson |
This season marks the start of a new seven-year rights agreement between Turner Sports and Major League Baseball including a season-long regular season slate and extended coverage of the MLB Postseason. TBS will serve as the exclusive home of the 2022 American League Division Series (ALDS) and American League Championship Series (ALCS). The current multimedia rights agreement extends the partnership between Turner Sports and MLB to more than 50 years. The partnership represents one of the longest-running relationships between a media company and league in the history of televised sports, dating back to 1973 when MLB games were first televised on WTCG (now TBS).