MLB on TBS Tuesday Night to Feature Aaron Judge and the New York Yankees in Consecutive Weeks – Tonight vs. Minnesota Twins and Sept. 13 at Boston Red Sox
| Date | Time (ET) | Program / Commentators |
| Sept. 6 | 6:30 p.m. | MLB on TBS Leadoff Pedro Martinez, Jimmy Rollins, Curtis Granderson & Ernie Johnson |
| 7 p.m. | Minnesota Twins* vs. New York Yankees Brian Anderson, Ron Darling & Lauren Shehadi | |
| Postgame | MLB on TBS Closer Martinez, Rollins, Granderson & Johnson |
| Date | Time (ET) | Program / Commentators |
| Sept. 13 | 6:30 p.m. | MLB on TBS Leadoff Martinez, Rollins, Granderson & Johnson |
| 7 p.m. | New York Yankees vs. Boston Red Sox* Anderson, Darling & Shehadi | |
| Postgame | MLB on TBS Closer Martinez, Rollins, Granderson & Johnson |
* = TBS telecast will be available in the local market
This season marks the start of a new seven-year rights agreement between Turner Sports and Major League Baseball including a season-long regular season slate and extended coverage of the MLB Postseason. TBS will serve as the exclusive home of the 2022 American League Division Series (ALDS) and American League Championship Series (ALCS). The current multimedia rights agreement extends the partnership between Turner Sports and MLB to more than 50 years. The partnership represents one of the longest-running relationships between a media company and league in the history of televised sports, dating back to 1973 when MLB games were first televised on WTCG (now TBS).